Cathepsin L2 antibody (Cleaved-Leu114)

Catalog No. ABIN1536113

The Rabbit Polyclonal anti-Cathepsin L2 antibody (ABIN1536113) specifically detects Cathepsin L2 in WB and ELISA. The antibody is reactive with Human and Monkey samples.

Quick Overview for Cathepsin L2 antibody (Cleaved-Leu114) (ABIN1536113)

Target: Cathepsin L2 (CTSL2)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cathepsin L2 Antibody

Binding Specificity: AA 95-144, Cleaved-Leu114

Purpose: Cleaved-Cathepsin L2 (L114) Antibody

Specificity: Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CATL2. AA range:95-144

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Alternative Name: CATL2

Background:

Synonyms: CTSL2, CATL2, CTSU, CTSV, Cathepsin L2, Cathepsin U, Cathepsin V

Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011],

Gene Name: CTSL2

Protein Name: Cathepsin L2

Molecular Weight: 37 kDa

Gene ID: 1515

OMIM: 603308

UniProt: O60911

Pathways: Toll-Like Receptors Cascades