Cathepsin Z antibody (Cleaved-Leu62)

Catalog No. ABIN1536114

This Rabbit Polyclonal antibody specifically detects Cathepsin Z in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for Cathepsin Z antibody (Cleaved-Leu62) (ABIN1536114)

Target: Cathepsin Z (CTSZ)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin Z antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cathepsin Z Antibody

Binding Specificity: AA 43-92, Cleaved-Leu62

Purpose: Cleaved-Cathepsin Z (L62) Antibody

Specificity: Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cathepsin Z

Target: Cathepsin Z (CTSZ)

Background:

Synonyms: CTSZ, Cathepsin Z, Cathepsin P, Cathepsin X

Background: The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008],

Gene Name: CTSZ

Protein Name: Cathepsin Z

Molecular Weight: 27 kDa

Gene ID: 1522

OMIM: 603169

UniProt: Q9UBR2

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones