Kallikrein 11 antibody (Cleaved-Ile54)

Catalog No. ABIN1536138

This Rabbit Polyclonal antibody specifically detects Kallikrein 11 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Kallikrein 11 antibody (Cleaved-Ile54) (ABIN1536138)

Target: Kallikrein 11 (KLK11)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Kallikrein 11 Antibody

Binding Specificity: AA 35-84, Cleaved-Ile54

Purpose: Cleaved-KLK11 (I54) Antibody

Specificity: Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Kallikrein-11. AA range:35-84

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Kallikrein 11

Target: Kallikrein 11 (KLK11)

Alternative Name: Kallikrein-11

Background:

Synonyms: KLK11, PRSS20, TLSP, Kallikrein-11, hK11, Hippostasin, Serine protease 20, Trypsin-like protease

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009],

Gene Name: KLK11

Protein Name: Kallikrein-11

Molecular Weight: 25 kDa

Gene ID: 11012

OMIM: 604434

UniProt: Q9UBX7

Pathways: Complement System