CTSA antibody (Cleaved-Arg326)

Catalog No. ABIN1536139

The Rabbit Polyclonal anti-CTSA antibody is suitable to detect CTSA in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for CTSA antibody (Cleaved-Arg326) (ABIN1536139)

Target: CTSA (Cathepsin A (CTSA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTSA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CTSA Antibody

Binding Specificity: AA 277-326, Cleaved-Arg326

Purpose: Cleaved-Cathepsin A 32k (R326) Antibody

Specificity: Cleaved-Cathepsin A 32k (R326) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin A 32k protein resulting from cleavage adjacent to R326.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PPGB. AA range:277-326

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CTSA

Target: CTSA (Cathepsin A (CTSA))

Alternative Name: PPGB

Background:

Synonyms: CTSA, PPGB, Lysosomal protective protein, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase

Background: This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015],

Gene Name: CTSA

Protein Name: Lysosomal protective protein

Molecular Weight: 33 kDa

Gene ID: 5476

OMIM: 613111

UniProt: P10619