OPN5 antibody (Cleaved-Val33)

Catalog No. ABIN1536148

The Rabbit Polyclonal anti-OPN5 antibody is suitable to detect OPN5 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for OPN5 antibody (Cleaved-Val33) (ABIN1536148)

Target: OPN5 (Opsin 5 (OPN5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPN5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OPN5 Antibody

Binding Specificity: AA 14-63, Cleaved-Val33

Purpose: Cleaved-KLK8 (V33) Antibody

Specificity: Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Neuropsin. AA range:14-63

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OPN5

Target: OPN5 (Opsin 5 (OPN5))

Alternative Name: Neuropsin

Background:

Synonyms: KLK8, NRPN, PRSS19, TADG14, Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],

Gene Name: KLK8

Protein Name: Kallikrein-8

Molecular Weight: 24 kDa

Gene ID: 11202

OMIM: 605644

UniProt: O60259