PARP1 antibody (Cleaved-Gly215)

Catalog No. ABIN1536153

This Rabbit Polyclonal antibody specifically detects PARP1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PARP1 antibody (Cleaved-Gly215) (ABIN1536153)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PARP1 Antibody

Binding Specificity: AA 196-245, Cleaved-Gly215

Specificity:

PARP (Cleaved-Gly215) Antibody detects endogenous levels of fragment of activated PARP resulting from cleavage adjacent to Gly215.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PARP.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:1000

Comment:

Unigene-Number: Hs.177766 (NCBI Gene Symbol: PARP1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP

Background:

Synonyms: ADP-ribosyltransferase 1, ADPRT, ADPRT1, pADPRT-1, PARP, PARP-1, poly (ADP-ribose) pol, poly [ADP-ribose] polymerase 1, poly[ADP-ribose] synthetase 1, PPOL

NCBI Gene Symbol: PARP1

Molecular Weight: 89 kDa

Gene ID: 142

OMIM: 173870

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location