Relaxin 2 antibody (C-Term)

Catalog No. ABIN1536713

Product Details anti-Relaxin 2 Antibody

Target: Relaxin 2 (RLN2)

Binding Specificity: AA 139-165, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-165 amino acids from the C-terminal region of human RLN2.

Clone: RB39661

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RLN2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Relaxin 2

Target: Relaxin 2 (RLN2)

Alternative Name: RLN2 (RLN2 Products)

Synonyms: H2 antibody, H2-RLX antibody, RLXH2 antibody, bA12D24.1.1 antibody, bA12D24.1.2 antibody, RFLX antibody, rln2 antibody, rln3c antibody, rlx3c antibody, si:rp71-39b20.5 antibody, relaxin 2 antibody, insulin-like 3 (Leydig cell) antibody, RLN2 antibody, insl3 antibody

Background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.

Molecular Weight: 21043

Gene ID: 6019

NCBI Accession: NP_005050, NP_604390

UniProt: P04090

Pathways: Hormone Activity