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NTAN1 antibody (C-Term)

NTAN1 Reactivity: Human WB Host: Rabbit Polyclonal RB37947 unconjugated
Catalog No. ABIN1536839
  • Target See all NTAN1 Antibodies
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    AA 203-230, C-Term
    Reactivity
    • 29
    • 9
    • 1
    Human
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NTAN1 antibody is un-conjugated
    Application
    • 17
    • 16
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human NTAN1.
    Clone
    RB37947
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NTAN1 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    NTAN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    Alternative Name
    NTAN1 (NTAN1 Products)
    Synonyms
    PNAA antibody, PNAD antibody, N-terminal Asn amidase antibody, N-terminal asparagine amidase antibody, Ntan1 antibody, NTAN1 antibody
    Background
    Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity).
    Gene ID
    123803
    NCBI Accession
    NP_001257695, NP_001257696, NP_775745
    UniProt
    Q96AB6
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