GEMIN8 antibody (C-Term)

Catalog No. ABIN1536854

The Rabbit Polyclonal anti-GEMIN8 antibody is suitable to detect GEMIN8 in samples from Human. It has been validated for WB.

Quick Overview for GEMIN8 antibody (C-Term) (ABIN1536854)

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN8 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB38258

Product Details anti-GEMIN8 Antibody

Binding Specificity: AA 213-239, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GEMIN8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for GEMIN8

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Alternative Name: GEMIN8

Background: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Molecular Weight: 28637

Gene ID: 54960

NCBI Accession: NP_001035944, NP_001035945, NP_060326

UniProt: Q9NWZ8

Pathways: Ribonucleoprotein Complex Subunit Organization