IL5RA antibody (C-Term)

Catalog No. ABIN1537258

This Rabbit Polyclonal antibody specifically detects IL5RA in WB. It exhibits reactivity toward Human.

Quick Overview for IL5RA antibody (C-Term) (ABIN1537258)

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL5RA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40195

Product Details anti-IL5RA Antibody

Binding Specificity: AA 391-420, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: IL5RA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Alternative Name: IL5RA

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Molecular Weight: 47685

Gene ID: 3568

NCBI Accession: NP_000555, NP_001230028, NP_783851, NP_783852, NP_783853, NP_783854, NP_783855

UniProt: Q01344

Pathways: JAK-STAT Signaling