RASA3 antibody (C-Term)

Catalog No. ABIN1537495

Product Details anti-RASA3 Antibody

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Binding Specificity: AA 594-623, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.

Clone: RB39648

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RASA3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Alternative Name: RASA3 (RASA3 Products)

Synonyms: rasa3 antibody, MGC82492 antibody, RASA3 antibody, gapiii antibody, gap1ip4bp antibody, LOC100222817 antibody, GAP1IP4BP antibody, GAPIII antibody, AI326412 antibody, C86362 antibody, E130011G04 antibody, scat antibody, R-ras gap antibody, RAS p21 protein activator 3 L homeolog antibody, RAS p21 protein activator 3 antibody, ras GTPase-activating protein 3 antibody, rasa3.L antibody, RASA3 antibody, rasa3 antibody, LOC100433573 antibody, Rasa3 antibody

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Molecular Weight: 95699

Gene ID: 22821

NCBI Accession: NP_031394

UniProt: Q14644