RASA3 antibody (C-Term)

Catalog No. ABIN1537495

This Rabbit Polyclonal antibody specifically detects RASA3 in WB. It exhibits reactivity toward Human.

Quick Overview for RASA3 antibody (C-Term) (ABIN1537495)

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39648

Product Details anti-RASA3 Antibody

Binding Specificity: AA 594-623, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RASA3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Alternative Name: RASA3

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Molecular Weight: 95699

Gene ID: 22821

NCBI Accession: NP_031394

UniProt: Q14644