HECTD3 antibody (C-Term)

Catalog No. ABIN1537576

This Rabbit Polyclonal antibody specifically detects HECTD3 in WB. It exhibits reactivity toward Human.

Quick Overview for HECTD3 antibody (C-Term) (ABIN1537576)

Target: HECTD3 (HECT Domain Containing 3 (HECTD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HECTD3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37186

Product Details anti-HECTD3 Antibody

Binding Specificity: AA 740-769, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HECTD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 740-769 amino acids from the C-terminal region of human HECTD3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HECTD3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for HECTD3

Target: HECTD3 (HECT Domain Containing 3 (HECTD3))

Alternative Name: HECTD3

Background: E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).

Molecular Weight: 97113

Gene ID: 79654

NCBI Accession: NP_078878

UniProt: Q5T447