Catalase antibody (AA 152-180)

Catalog No. ABIN1537700

The Mouse Monoclonal anti-Catalase antibody has been validated for WB. It is suitable to detect Catalase in samples from Human and Mouse. There is 1 publication available.

Quick Overview for Catalase antibody (AA 152-180) (ABIN1537700)

Target: Catalase (CAT)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Catalase antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 626CT4-3-8

Product Details anti-Catalase Antibody

Binding Specificity: AA 152-180

Predicted Reactivity: B, Zf, Pig, Rat

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1600. WB: 1:1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CAT Antibody (Center)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-Catalase antibody (ABIN1537700)

Pereira, Igea, Canovas, Dolado, Nebreda: "Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1759-74, (2013) (PubMed).

Target Details for Catalase

Target: Catalase (CAT)

Alternative Name: CAT

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molecular Weight: 59756

Gene ID: 847

NCBI Accession: NP_001743

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism