PPIL5 antibody (AA 127-153)

Catalog No. ABIN1537806

Product Details anti-PPIL5 Antibody

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Binding Specificity: AA 127-153

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIL5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPIL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5.

Clone: RB38338

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PPIL5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PPIL5

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Alternative Name: PPIL5 (LRR1 Products)

Synonyms: 2410005L11Rik antibody, AU021780 antibody, LRR-1 antibody, Ppil5 antibody, 4-1BBLRR antibody, PPIL5 antibody, leucine rich repeat protein 1 antibody, Lrr1 antibody, LRR1 antibody

Background: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight: 46723

Gene ID: 122769

NCBI Accession: NP_689542, NP_982292

UniProt: Q96L50