DUSP12 antibody (AA 162-191)

Catalog No. ABIN1537912

This Rabbit Polyclonal antibody specifically detects DUSP12 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for DUSP12 antibody (AA 162-191) (ABIN1537912)

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB35761

Product Details anti-DUSP12 Antibody

Binding Specificity: AA 162-191

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DUSP12 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Alternative Name: DUSP12

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Molecular Weight: 37687

Gene ID: 11266

NCBI Accession: NP_009171

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process