PCDHGB4 antibody (AA 353-379)

Catalog No. ABIN1538347

This Rabbit Polyclonal antibody specifically detects PCDHGB4 in WB. It exhibits reactivity toward Human.

Quick Overview for PCDHGB4 antibody (AA 353-379) (ABIN1538347)

Target: PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGB4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39608

Product Details anti-PCDHGB4 Antibody

Binding Specificity: AA 353-379

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCDHGB4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PCDHGB4

Target: PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

Alternative Name: PCDHGB4

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.

Molecular Weight: 99927

Gene ID: 8641

NCBI Accession: NP_003727, NP_115269

UniProt: Q9UN71