High Mobility Group B Protein 4 (HMGB4) (AA 45-73) antibody

Catalog No. ABIN1538426

The Rabbit Polyclonal anti-High Mobility Group B Protein 4 antibody is suitable to detect High Mobility Group B Protein 4 in samples from Human. It has been validated for WB.

Quick Overview for High Mobility Group B Protein 4 (HMGB4) (AA 45-73) antibody (ABIN1538426)

Target: High Mobility Group B Protein 4 (HMGB4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Clone: RB37932

Product Details

Binding Specificity: AA 45-73

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HMGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human HMGB4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HMGB4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details

Target: High Mobility Group B Protein 4 (HMGB4)

Alternative Name: HMGB4

Background: High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

Molecular Weight: 22490

Gene ID: 127540

NCBI Accession: NP_660206

UniProt: Q8WW32