TNNI3 antibody (AA 86-114)
Quick Overview for TNNI3 antibody (AA 86-114) (ABIN1538664)
Target
See all TNNI3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 86-114
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TNNI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human TNNI3.
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Isotype
- IgG
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- TNNI3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Expiry Date
- 6 months
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- TNNI3 (Cardiac Troponin I (TNNI3))
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Alternative Name
- TNNI3
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Background
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
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Molecular Weight
- 24008
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Gene ID
- 7137
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NCBI Accession
- NP_000354
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UniProt
- P19429
Target
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