PDCD10 antibody (AA 96-124)
Quick Overview for PDCD10 antibody (AA 96-124) (ABIN1538712)
Target
See all PDCD10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 96-124
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Predicted Reactivity
- Zf, C, M, Rat, X
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- PDCD10 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Expiry Date
- 6 months
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- PDCD10 (Programmed Cell Death 10 (PDCD10))
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Alternative Name
- PDCD10
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Background
- This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
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Molecular Weight
- 24702
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Gene ID
- 11235
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NCBI Accession
- NP_009148, NP_665858, NP_665859
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UniProt
- Q9BUL8
Target
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