Gelsolin antibody (N-Term)

Catalog No. ABIN1538731

This Mouse Monoclonal antibody specifically detects Gelsolin in WB. It exhibits reactivity toward Human.

Quick Overview for Gelsolin antibody (N-Term) (ABIN1538731)

Target: Gelsolin (GSN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 328CT2-2-1

Product Details anti-Gelsolin Antibody

Binding Specificity: AA 230-259, N-Term

Predicted Reactivity: B

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:1000. WB: 1:100~500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: GSN Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background: The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Molecular Weight: 85698

Gene ID: 2934

NCBI Accession: NP_000168, NP_001121134, NP_001121135, NP_001121136, NP_001121137, NP_001121138, NP_001121139, NP_001244958, NP_001244959, NP_937895

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy