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ITM2C antibody (N-Term)

ITM2C Reactivity: Human WB Host: Rabbit Polyclonal RB36714 unconjugated
Catalog No. ABIN1539240
  • Target See all ITM2C Antibodies
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-55, N-Term
    Reactivity
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITM2C antibody is un-conjugated
    Application
    • 33
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Pr
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.
    Clone
    RB36714
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    ITM2C Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Alternative Name
    ITM2C (ITM2C Products)
    Synonyms
    3110038L02Rik antibody, BRI3 antibody, Bricd2c antibody, E25 antibody, E25C antibody, ITM3 antibody, BRICD2C antibody, fj35c02 antibody, itm2c antibody, wu:fj35c02 antibody, zgc:66349 antibody, wu:fj52a04 antibody, zgc:92783 antibody, integral membrane protein 2C antibody, integral membrane protein 2Cb antibody, integral membrane protein 2Ca antibody, Itm2c antibody, ITM2C antibody, itm2cb antibody, itm2ca antibody
    Background
    Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
    Molecular Weight
    30224
    Gene ID
    81618
    NCBI Accession
    NP_001012532, NP_001012534, NP_112188
    UniProt
    Q9NQX7
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