Syndecan 1 antibody (C-Term)

Catalog No. ABIN1539995

The Mouse Monoclonal anti-Syndecan 1 antibody has been validated for WB, FACS and IF. It is suitable to detect Syndecan 1 in samples from Human. There is 1 publication available.

Quick Overview for Syndecan 1 antibody (C-Term) (ABIN1539995)

Target: Syndecan 1 (SDC1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Syndecan 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 587CT7-3-6-5

Product Details anti-Syndecan 1 Antibody

Binding Specificity: AA 210-238, C-Term

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CD138 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.

Isotype: IgM

Application Details

Application Notes: IF: 1:10~50. IF: 1:10~50. IF: 1:10~50. WB: 1:500~8000. FC: 1:10~50. FC: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CD138 Antibody (C-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-Syndecan 1 antibody (ABIN1539995)

Chen, Zou, Zong, Meng, An, Yang: "Anti-human CD138 monoclonal antibodies and their bispecific formats: generation and characterization." in: Immunopharmacology and immunotoxicology, Vol. 38, Issue 3, pp. 175-83, (2017) (PubMed).

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: CD138

Background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Molecular Weight: 32462

Gene ID: 6382

NCBI Accession: NP_001006947, NP_002988

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism