Calpain 2 antibody (C-Term)

Catalog No. ABIN155111

The Rabbit Polyclonal anti-Calpain 2 antibody has been validated for WB. It is suitable to detect Calpain 2 in samples from Human, Mouse and Rat.

Quick Overview for Calpain 2 antibody (C-Term) (ABIN155111)

Target: Calpain 2 (CAPN2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calpain 2 Antibody

Binding Specificity: C-Term

Specificity: The anti-calpain-2 antibody recognizes the 80 kDa Calpain-2. It does not cross-react with other calpains.

Purification: Affinity purified

Immunogen: Synthetic peptide mapping to the C-terminus of the domain III of human Calpain-2 large subunit

Application Details

Application Notes: Western Blot: 1: 200-1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: Calpain-2

Background: Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Calpain-1 and 2 consist of a common small subunit and a large variable subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF-hand domain IV. Type I calpain requires micromolar amounts of calcium, while type II calpain requires millimolar amounts of calcium.Synonyms: CANP2, CANPL2, CAPN2, Calcium-activated neutral proteinase 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 catalytic subunit, Calpain-2 large subunit, M-calpain, Millimolar-calpain

Gene ID: 824

NCBI Accession: NP_001139540

UniProt: P17655