Calpain 2 antibody (AA 301-335)

Catalog No. ABIN6244178

Product Details anti-Calpain 2 Antibody

Target: Calpain 2 (CAPN2)

Binding Specificity: AA 301-335

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CAPN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 301-335 amino acids from the Central region of human CAPN2.

Clone: RB52877

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Calpain 2 antibody (ABIN6244178)

Zhao, Cui, Zhou, Li, Zhang, Sun, Han, Zou, Wang, Li, Wang: "Calpain-Calcineurin-Nuclear Factor Signaling and the Development of Atrial Fibrillation in Patients with Valvular Heart Disease and Diabetes." in: Journal of diabetes research, Vol. 2016, pp. 4639654, (2016) (PubMed).

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: CAPN2 (CAPN2 Products)

Background: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:< a href="http://www.uniprot.org/citations/17650508" target="_blank">17650508).

Molecular Weight: 79995

UniProt: P17655