TFG antibody

Catalog No. ABIN1558081

This Mouse Monoclonal antibody specifically detects TFG in WB, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for TFG antibody (ABIN1558081)

Target: TFG (Trk-Fused Gene (TFG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: TFG-03

Product Details anti-TFG Antibody

Purpose: Anti-TFG Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human recombinant protein Trx-his-NTFG

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for TFG

Target: TFG (Trk-Fused Gene (TFG))

Alternative Name: TFG

Background: Trafficking from ER to golgi regulator,TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.,TF6, TRKT3, SPG57

Gene ID: 10342

UniProt: Q92734