LRP2 antibody

Catalog No. ABIN1589720

The Mouse Monoclonal anti-LRP2 antibody has been validated for IHC and IF. It is suitable to detect LRP2 in samples from Human.

Quick Overview for LRP2 antibody (ABIN1589720)

Target: LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: CD7D5

Product Details anti-LRP2 Antibody

Specificity: Purified human Megalin

Cross-Reactivity: Rat (Rattus), Mouse (Murine)

Characteristics: Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.

Isotype: IgG1

Application Details

Application Notes: IF/ IHC: use at 2-5 µg/mL

Comment:

Monoclonal Antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: -20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for LRP2

Target: LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

Alternative Name: Megalin

Background: Megalin/gp330, an approx. 600 kDa transmembrane glycoprotein is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease:protease inhibitor families.
Synonyms: LRP2, DBS, GP330, low density lipoprotein receptor-related protein 2, Glycoprotein 330

Molecular Weight: 600 kDa

NCBI Accession: NP_004516, NM_004525

UniProt: P98164

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport