LRP2 antibody (AA 3401-3500)

Catalog No. ABIN750988

This Rabbit Polyclonal antibody specifically detects LRP2 in FACS, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for LRP2 antibody (AA 3401-3500) (ABIN750988)

Target: LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LRP2 Antibody

Binding Specificity: AA 3401-3500

Purpose: LRP2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Megalin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LRP2 antibody (ABIN750988)

Erikci, Ucar, Yabanoglu-Ciftci: "Role of serotonin in the regulation of renal proximal tubular epithelial cells." in: Renal failure, Vol. 38, Issue 7, pp. 1141-50, (2016) (PubMed).

Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." in: Biology of sex differences, Vol. 6, pp. 2, (2015) (PubMed).

Target Details for LRP2

Target: LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

Alternative Name: Lrp2/Megalin

Background:

Synonyms: DBS, GP33, Low-density lipoprotein receptor-related protein 2, LRP-2, Glycoprotein 33, Megalin, LRP2

Background: Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.

Gene ID: 4036

UniProt: P98164

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport