PROX1 antibody (Biotin)

Catalog No. ABIN1589721

This anti-PROX1 antibody is a Rabbit Polyclonal antibody detecting PROX1 in IF. Suitable for Human.

Quick Overview for PROX1 antibody (Biotin) (ABIN1589721)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROX1 antibody is conjugated to Biotin

Application: Immunofluorescence (IF)

Product Details anti-PROX1 Antibody (Biotin)

Specificity: Recombinant human Prox-1

Characteristics: Chromosomal location: 1q32.2-q32.3

Isotype: IgG

Application Details

Application Notes: IF/IHC: use at 1-5 µg/mL.

Comment:

Rabbit IG Polyclonal Antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, BSA (50x), 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Centrifuge vial prior to opening.

Storage: -20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Alternative Name: Prox-1

Background: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lymphatic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Produced from sera of rabbits immunized with the recombinant highly conserved C-terminal part of the homeobox transcription factor Prox-1.
Synonyms: PROX1, W117m

NCBI Accession: NP_002754, NM_002763

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation