EGFL7 antibody

Catalog No. ABIN1589865

Product Details anti-EGFL7 Antibody

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGFL7 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recombinant mouse EGFL-7

Characteristics: Chromosomal location: 2, 2 B
Produced from sera of rabbits immunized with highly pure recombinant mouse EGFL-7derived from E. Coli.

Isotype: IgG

Application Details

Application Notes: Western Blot: use 1-5 µg/mL.

Comment:

Rabbit IG Polyclonal Antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: -20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for EGFL7

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Alternative Name: VE-Statin/EGFL-7 (EGFL7 Products)

Synonyms: egfl7 antibody, MGC53105 antibody, EGFL7 antibody, zgc:136669 antibody, zgc:152804 antibody, zneu1 antibody, xegfl7 antibody, MGC147423 antibody, VE-statin antibody, Zneu1 antibody, NEU1 antibody, RP11-251M1.2 antibody, VE-STATIN antibody, ZNEU1 antibody, EGF like domain multiple 7 S homeolog antibody, EGF like domain multiple 7 antibody, EGF-like-domain, multiple 7 antibody, EGF-like domain 7 antibody, egfl7.S antibody, EGFL7 antibody, egfl7 antibody, Egfl7 antibody

Background: EGFL7 is an ∼ 30 kDa secreted protein that contain an Emilin-like (EMI) domain (a multimerization motif), and 2 epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms: Egfl7, EGF-like domain 7, Zneu1, VE-statin

NCBI Accession: NP_942018, NM_198725

UniProt: Q9QXT5