Emilin1 antibody

Catalog No. ABIN1589875

This Rat Monoclonal antibody specifically detects Emilin1 in WB and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for Emilin1 antibody (ABIN1589875)

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Emilin1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: C11A8

Product Details anti-Emilin1 Antibody

Purpose: Emilin-1 antibody

Specificity: Recombinant mouse Emilin-1

Characteristics: Chromosomal location: 5 B1, 5

Purification: Protein-G purified

Immunogen: Recombinant mouse Emilin-1

Application Details

Application Notes: Western Blot: use at 2-10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Expiry Date: 24 months

Target Details for Emilin1

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Alternative Name: Emilin-1

Background: Gp115, AW229038, BB105748, EMILIN-1, 5830419M17Rik, elastin microfibril interface located protein 1,Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.

Gene ID: 100952

NCBI Accession: NM_133918, NP_598679

UniProt: Q99K41