BMP2 antibody

Catalog No. ABIN1589877

This anti-BMP2 antibody is a Rabbit Polyclonal antibody detecting BMP2 in WB and ELISA. Suitable for Human.

Quick Overview for BMP2 antibody (ABIN1589877)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMP2 Antibody

Purpose: BMP-2 antibody

Specificity: Recombinant human BMP-2

Characteristics: Chromosomal location: 20p12
Anti-human BMP-2/4 polyclonal serum was produced from sera of rabbits pre- immunized with a highly purified synthetic peptide of the human BMP-2/4 sequence (C-terminal amino acids “C(SH)-L-D-E-Y-D-K-V-V-L-K-N-Y-Q-E-M-V-V-E-G“).

Purification: Anti-human BMP-2/4 polyclonal antiserum was purified by Protein A chromatography.

Immunogen: Recombinant human BMP-2

Isotype: IgG

Application Details

Application Notes: Western Blot: Use 2-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Expiry Date: 24 months

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP-2

Background: Bone morphogenetic protein 2, BDA2, BMP2A, bone morphogenetic protein 4, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6,Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. The antibody cross-reacts displays cross-reaction with human BMP-4 monomers in Western Blot.

Gene ID: 650

NCBI Accession: NM_001200, NP_001191

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation