CXCR4 antibody (N-Term)

Catalog No. ABIN1589897

This Rabbit Polyclonal antibody specifically detects CXCR4 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CXCR4 antibody (N-Term) (ABIN1589897)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CXCR4 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-Human CXCR4 Polyclonal Antibody

Specificity: Recombinant human CXCR4 fusion protein [N-terminal and loops]

Characteristics: Chromosomal location: 2q21
Produced from sera of rabbits immunized with highly pure recombinant human CXCR4 fusion protein [N-terminal and extracellular loops] produced in E. Coli.

Purification: Protein A purified

Immunogen: Recombinant human CXCR4 fusion protein [N-terminal and loops]

Isotype: IgG

Application Details

Application Notes: Western Blot: Use 2-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Expiry Date: 24 months

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background:

Synonyms: CXCR4, FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E

Description: Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently six CXC-specific receptors designated CXCR1 to CXCR6.

Gene ID: 7852

NCBI Accession: NM_001008540, NP_001008540

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events