TLR7 antibody (AA 451-500)

Catalog No. ABIN165464

The Mouse Monoclonal anti-TLR7 antibody has been validated for ELISA, FACS, ICC and IF. It is suitable to detect TLR7 in samples from Human.

Quick Overview for TLR7 antibody (AA 451-500) (ABIN165464)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 4F4

Product Details anti-TLR7 Antibody

Binding Specificity: AA 451-500

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human TLR7 (451-500aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7

Background: TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7 (hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7, 8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.

NCBI Accession: NP_057646

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades