PHD1 antibody

Catalog No. ABIN1678674

The Rabbit Monoclonal anti-PHD1 antibody (ABIN1678674) specifically detects PHD1 in WB. The antibody is reactive with Human samples.

Quick Overview for PHD1 antibody (ABIN1678674)

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHD1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Prolyl hydroxylase PHD1 (EGLN2)

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHD1

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Alternative Name: EGLN2

Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011],EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Hypoxia,Invasion and Metastasis,EGLN2

Molecular Weight: 44 kDa

Gene ID: 112398

UniProt: Q96KS0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis