TSC1 antibody

Catalog No. ABIN1678705

This Rabbit Monoclonal antibody specifically detects TSC1 in WB. It exhibits reactivity toward Human.

Quick Overview for TSC1 antibody (ABIN1678705)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSC1 Antibody

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Hamartin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Alternative Name: TSC1

Background: This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009],LAM, TSC,AMPK Signaling Pathway,Apoptosis,Autophagy,Autophagy_Regulator,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Epigenetics & Nuclear Signaling,Insulin Receptor Signaling Pathway,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Akt downstream targets,Signal Transduction,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Tumor suppressors,TSC1

Molecular Weight: 150 kDa

Gene ID: 7248

UniProt: Q92574

Pathways: RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation