ATP6V1E1 antibody (AA 77-226)

Catalog No. ABIN1678795

This Rabbit Polyclonal antibody specifically detects ATP6V1E1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ATP6V1E1 antibody (AA 77-226) (ABIN1678795)

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATP6V1E1 Antibody

Binding Specificity: AA 77-226

Sequence: NQARLKVLRA RDDLITDLLN EAKQRLSKVV KDTTRYQVLL DGLVLQGLYQ LLEPRMIVRC RKQDFPLVKA AVQKAIPMYK IATKNDVDVQ IDQESYLPED IAGGVEIYNG DRKIKVSNTL ESRLDLIAQQ MMPEVRGALF GANANRKFLD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V1E1

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Alternative Name: ATP6V1E1

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.,ATP6V1E1,ATP6E,ATP6E2,ATP6V1E,P31,Vma4,ARCL2C,Cancer,Signal Transduction,Endocrine & Metabolism,ATP6V1E1

Molecular Weight: 22 kDa/23 kDa/26 kDa

Gene ID: 529

UniProt: P36543

Pathways: Transition Metal Ion Homeostasis, Proton Transport