TSPO antibody

Catalog No. ABIN1679051

The Rabbit Monoclonal anti-TSPO antibody has been validated for WB, IHC and IF. It is suitable to detect TSPO in samples from Human.

Quick Overview for TSPO antibody (ABIN1679051)

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TSPO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TSPO Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PBR/TSPO

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TSPO

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Alternative Name: TSPO

Background: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported, one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012],BPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, mDRC, pk18,Apoptosis,Calcium Signaling,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Neuroscience,Signal Transduction,TSPO

Molecular Weight: 18 kDa

Gene ID: 706

UniProt: P30536

Pathways: Cellular Response to Molecule of Bacterial Origin