DMC1 antibody (AA 1-260)

Catalog No. ABIN1679545

This Rabbit Polyclonal antibody specifically detects DMC1 in WB. It exhibits reactivity toward Human.

Quick Overview for DMC1 antibody (AA 1-260) (ABIN1679545)

Target: DMC1 (DNA Meiotic Recombinase 1 (DMC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DMC1 Antibody

Binding Specificity: AA 1-260

Sequence: MKEDQVVAEE PGFQDEEESL FQDIDLLQKH GINVADIKKL KSVGICTIKG IQMTTRRALC NVKGLSEAKV DKIKEAANKL IEPGFLTAFE YSEKRKMVFH ITTGSQEFDK LLGGGIESMA ITEAFGEFRT GKTQLSHTLC VTAQLPGAGG YPGGKIIFID TENTFRPDRL RDIADRFNVD HDAVLDNVLY ARAYTSEHQM ELLDYVAAKF HEEAGIFKLL IIDSIMALFR VDFSGRGELA ERQQKLAQML SRLQKISEEY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DMC1 (NP_008999.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DMC1

Target: DMC1 (DNA Meiotic Recombinase 1 (DMC1))

Alternative Name: DMC1

Background: This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.,DMC1,DMC1H,LIM15,dJ199H16.1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,DMC1

Molecular Weight: 31 kDa/37 kDa

Gene ID: 11144

UniProt: Q14565