EDNRB antibody (AA 1-100)

Catalog No. ABIN1679650

This anti-EDNRB antibody is a Rabbit Polyclonal antibody detecting EDNRB in WB. Suitable for Human.

Quick Overview for EDNRB antibody (AA 1-100) (ABIN1679650)

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDNRB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EDNRB Antibody

Binding Specificity: AA 1-100

Sequence: MQPPPSLCGR ALVALVLACG LSRIWGEERG FPPDRATPLL QTAEIMTPPT KTLWPKGSNA SLARSLAPAE VPKGDRTAGS PPRTISPPPC QGPIEIKETF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human EDNRB (NP_001116131.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDNRB

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Alternative Name: EDNRB

Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,EDNRB,ABCDS,ET-B,ET-BR,ETB,ETB1,ETBR,ETRB,HSCR,HSCR2,WS4A,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),EDNRB

Molecular Weight: 48 kDa/49 kDa/59 kDa

Gene ID: 1910

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process