FANCI antibody (AA 1061-1328)

Catalog No. ABIN1679817

This anti-FANCI antibody is a Rabbit Polyclonal antibody detecting FANCI in WB. Suitable for Human.

Quick Overview for FANCI antibody (AA 1061-1328) (ABIN1679817)

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FANCI Antibody

Binding Specificity: AA 1061-1328

Sequence: DQDVEVEKTN HFAIVNLRTA APTVCLLVLS QAEKVLEEVD WLITKLKGQV SQETLSEEAS SQATLPNQPV EKAIIMQLGT LLTFFHELVQ TALPSGSCVD TLLKDLCKMY TTLTALVRYY LQVCQSSGGI PKNMEKLVKL SGSHLTPLCY SFISYVQNKS KSLNYTGEKK EKPAAVATAM ARVLRETKPI PNLIFAIEQY EKFLIHLSKK SKVNLMQHMK LSTSRDFKIK GNILDMVLRE DGEDENEEGT ASEHGGQNKE PAKKKRKK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1061-1328 of human FANCI (NP_001106849.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Alternative Name: FANCI

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.,FANCI,KIAA1794,Epigenetics & Nuclear Signaling,DNA Damage & Repair,FANCI

Molecular Weight: 27 kDa/142 kDa/149 kDa

Gene ID: 55215

UniProt: Q9NVI1

Pathways: DNA Damage Repair