GALC antibody (AA 40-300)

Catalog No. ABIN1679950

This Rabbit Polyclonal antibody specifically detects GALC in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for GALC antibody (AA 40-300) (ABIN1679950)

Target: GALC (Galactosylceramidase (GALC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GALC Antibody

Binding Specificity: AA 40-300

Sequence: GGAYVLDDSD GLGREFDGIG AVSGGGATSR LLVNYPEPYR SQILDYLFKP NFGASLHILK VEIGGDGQTT DGTEPSHMHY ALDENYFRGY EWWLMKEAKK RNPNITLIGL PWSFPGWLGK GFDWPYVNLQ LTAYYVVTWI VGAKRYHDLD IDYIGIWNER SYNANYIKIL RKMLNYQGLQ RVKIIASDNL WESISASMLL DAELFKVVDV IGAHYPGTHS AKDAKLTGKK LWSSEDFSTL NSDMGAGCWG RILNQNYING Y

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GALC

Target: GALC (Galactosylceramidase (GALC))

Alternative Name: GALC

Background: This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,GALC,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Cardiovascular,Lipids,Neuron marker,GALC

Molecular Weight: 67 kDa/74 kDa/77 kDa

Gene ID: 2581

UniProt: P54803