ITGAL antibody (AA 26-306)

Catalog No. ABIN3015542

This Rabbit Polyclonal antibody specifically detects ITGAL in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ITGAL antibody (AA 26-306) (ABIN3015542)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ITGAL Antibody

Binding Specificity: AA 26-306

Sequence: YNLDVRGARS FSPPRAGRHF GYRVLQVGNG VIVGAPGEGN STGSLYQCQS GTGHCLPVTL RGSNYTSKYL GMTLATDPTD GSILFAAVQF STSYKTEFDF SDYVKRKDPD ALLKHVKHML LLTNTFGAIN YVATEVFREE LGARPDATKV LIIITDGEAT DSGNIDAAKD IIRYIIGIGK HFQTKESQET LHKFASKPAS EFVKILDTFE KLKDLFTELQ KKIYVIEGTS KQDLTSFNME LSSSGISADL SRGHAVVGAV GAKDWAGGFL DLKADLQDDT F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD11a/LFA-1A/ITGAL (NP_001107852.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: ITGAL

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.,CD11A,LFA-1,LFA1A,CD11a,ITGAL,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,ITGAL

Molecular Weight: 119 kDa/128 kDa/134 kDa

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex