PRMT5 antibody (C-Term)

Catalog No. ABIN1682308

This Rabbit Polyclonal antibody specifically detects PRMT5 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for PRMT5 antibody (C-Term) (ABIN1682308)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PRMT5 Antibody

Binding Specificity: C-Term

Sequence: MPYVVRLHNF HQLSAPQPCF TFSHPNRDPM IDNNRYCTLE FPVEVNTVLH GFAGYFETVL YQDITLSIRP ETHSPGMFSW FPILFPIKQP ITVREGQTIC VRFWRCSNSK KVWYEWAVTA PVCSAIHNPT GRSYTIGL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human PRMT5 (NP_006100.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Alternative Name: PRMT5

Background: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.,HRMT1L5,IBP72,JBP1,SKB1,SKB1Hs,PRMT5,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,PRMT5

Molecular Weight: 53 kDa/66 kDa/67 kDa/71 kDa/72 kDa

Gene ID: 10419

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development