ROR1 antibody (AA 30-200)

Catalog No. ABIN1682562

The Rabbit Polyclonal anti-ROR1 antibody (ABIN1682562) specifically detects ROR1 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for ROR1 antibody (AA 30-200) (ABIN1682562)

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ROR1 Antibody

Binding Specificity: AA 30-200

Sequence: QETELSVSAE LVPTSSWNIS SELNKDSYLT LDEPMNNITT SLGQTAELHC KVSGNPPPTI RWFKNDAPVV QEPRRLSFRS TIYGSRLRIR NLDTTDTGYF QCVATNGKEV VSSTGVLFVK FGPPPTASPG YSDEYEEDGF CQPYRGIACA RFIGNRTVYM ESLHMQGEIE N

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human ROR1 (NP_005003.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ROR1

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Alternative Name: ROR1

Background: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.,ROR1,NTRKR1,dJ537F10.1,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,ROR1

Molecular Weight: 42 kDa/43 kDa/104 kDa

Gene ID: 4919

UniProt: Q01973

Pathways: RTK Signaling, WNT Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha