SAP18 antibody (AA 21-172)

Catalog No. ABIN1682621

The Rabbit Polyclonal anti-SAP18 antibody has been validated for WB, IHC and IF. It is suitable to detect SAP18 in samples from Human.

Quick Overview for SAP18 antibody (AA 21-172) (ABIN1682621)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SAP18 Antibody

Binding Specificity: AA 21-172

Sequence: AVESRVTQEE IKKEPEKPID REKTCPLLLR VFTTNNGRHH RMDEFSRGNV PSSELQIYTW MDATLKELTS LVKEVYPEAR KKGTHFNFAI VFTDVKRPGY RVKEIGSTMS GRKGTDDSMT LQSQKFQIGD YLDIAITPPN RAPPPSGRMR PY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18 (NP_005861.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.,SAP18,2HOR0202,SAP18P,Epigenetics & Nuclear Signaling,SAP18

Molecular Weight: 17 kDa

Gene ID: 10284

UniProt: O00422