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SAP18 antibody (N-Term)

SAP18 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780718
  • Target See all SAP18 Antibodies
    SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 29
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 26
    • 3
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    This SAP18 antibody is un-conjugated
    Application
    • 26
    • 18
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against SAP18. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SAP18
    Top Product
    Discover our top product SAP18 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 153 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
    Alternative Name
    SAP18 (SAP18 Products)
    Synonyms
    zgc:73118 antibody, C530046K05Rik antibody, D11Ertd539e antibody, EMegR4 antibody, Sinbp1 antibody, 2HOR0202 antibody, SAP18P antibody, Sin3A-associated protein antibody, Sin3-associated polypeptide 18 antibody, Sin3A associated protein 18 antibody, Sin3A associated protein 18kDa S homeolog antibody, sap18 antibody, Sap18 antibody, sap18.S antibody, SAP18 antibody
    Background
    Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
    Alias Symbols: SAP18P, 2HOR0202
    Protein Interaction Partner: INCA1, RBM39, UBC, RNF2, SUZ12, BMI1, CSNK2A2, MAGOH, EIF4A3, VCP, NFIA, SEPT2, MYO1C, IK, HNRNPU, HNRNPC, GTF3C1, SEPT7, CDC5L, U2AF1, SNRPD2, SMARCC2, SMARCB1, SRSF7, SRSF5, SRSF3, SRSF1, SAFB, S100A9, PSAP, NHP2L1, TPR, TFPI, SURF4, SSRP1, SSR3, LOC255
    Protein Size: 153
    Molecular Weight
    18 kDa
    Gene ID
    10284
    NCBI Accession
    NM_005870, NP_005861
    UniProt
    O00422
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