SGCA antibody (AA 60-290)

Catalog No. ABIN1682687

The Rabbit Polyclonal anti-SGCA antibody is suitable to detect SGCA in samples from Human. It has been validated for WB and IF.

Quick Overview for SGCA antibody (AA 60-290) (ABIN1682687)

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SGCA Antibody

Binding Specificity: AA 60-290

Sequence: ITYHAHLQGH PDLPRWLRYT QRSPHHPGFL YGSATPEDRG LQVIEVTAYN RDSFDTTRQR LVLEIGDPEG PLLPYQAEFL VRSHDAEEVL PSTPASRFLS ALGGLWEPGE LQLLNVTSAL DRGGRVPLPI EGRKEGVYIK VGSASPFSTC LKMVASPDSH ARCAQGQPPL LSCYDTLAPH FRVDWCNVTL VDKSVPEPAD EVPTPGDGIL EHDPFFCPPT EAPDRDFLVD A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 of human alpha Sarcoglycan (alpha Sarcoglycan (SGCA)) (NP_000014.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SGCA

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Alternative Name: SGCA

Background: This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.,SGCA,50DAG,ADL,DAG2,DMDA2,LGMD2D,SCARMD1,adhalin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,SGCA

Molecular Weight: 29 kDa/42 kDa

Gene ID: 6442

UniProt: Q16586