PRAS40 antibody

Catalog No. ABIN3017774

This Rabbit Monoclonal antibody specifically detects PRAS40 in WB. It exhibits reactivity toward Human.

Quick Overview for PRAS40 antibody (ABIN3017774)

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRAS40 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRAS40 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human AKT1S1/AKT1S1/PRAS40

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Alternative Name: AKT1S1

Background: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],Lobe, PRAS40,Apoptosis,Autophagy,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Kinase,mTOR Signaling Pathway,Neuroscience,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Akt downstream targets,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,AKT1S1

Molecular Weight: 40 kDa

Gene ID: 84335

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect