ERCC6 antibody (AA 717-731)

Catalog No. ABIN1686785

The Goat Polyclonal anti-ERCC6 antibody has been validated for WB and ELISA. It is suitable to detect ERCC6 in samples from Human.

Quick Overview for ERCC6 antibody (AA 717-731) (ABIN1686785)

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ERCC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-ERCC6 Antibody

Binding Specificity: AA 717-731

Purpose: ERCC6 (aa717-731)

Sequence: SNASPVQVKT AYKCA

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 170 kDa band observed in nuclear lysates of cell line HeLa (calculated MW of 168 kDa according to NP_000115.1). Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for ERCC6

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Alternative Name: ERCC6

Background: ERCC6, excision repair cross-complementing rodent repair deficiency, complementation group 6, ARMD5, CKN2, COFS, COFS1, CSB, RAD26, ATP-dependent helicase ERCC6, Cockayne syndrome B protein, Cockayne syndrome group B protein, DNA excision repair protein E

Molecular Weight: 170 kDa

Gene ID: 2074, 319955, 306274

NCBI Accession: NP_000115

Pathways: DNA Damage Repair, Chromatin Binding