Orexin A antibody (AbBy Fluor® 350)

Catalog No. ABIN1692795

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-Orexin A antibody (ABIN1692795) specifically detects Orexin A in WB and IF (p). The antibody is reactive with Human samples.

Quick Overview for Orexin A antibody (AbBy Fluor® 350) (ABIN1692795)

Target: Orexin A (OXA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Orexin A antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Orexin A Antibody (AbBy Fluor® 350)

Purpose: Orexin A Polyclonal Antibody, AbBy Fluor-350 Conjugated

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Orexin A

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Orexin A

Target: Orexin A (OXA)

Alternative Name: Orexin A

Background:

Synonyms: HCRT 1, HCRT, HCRT1, HCRT2, Hypocretin orexin neuropeptide precursor, Hypocretin 1, Hypocretin 2, Hypocretin A, Hypocretin, Hypocretin neuropeptide precursor, Hypocretin1, NRCLP1, Orexin A, Orexin, Orexin B, Orexin precursor, OrexinA, OX, PPORX, PPOX, PREPROOREXIN, OREX_HUMAN.

Background: Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

Gene ID: 3060

Pathways: Synaptic Membrane, Feeding Behaviour